Storing insulin at the right temperature is essential to ensure it does its job - lowering your blood sugar levels efficiently.

But life happens, and we've all accidentally left our insulin out of the fridge at least once. Whether it's forgotten on the kitchen counter or inadvertently left in a bag, understanding the risks associated with insulin that's been left out for too long is key for your diabetes management.

So, let's dive into some of the most pressing questions you might have:

  • What happens when insulin is left out of the refrigerator?
  • How long can it be left out?
  • Can you use insulin that's been left out for too long or is it ruined?
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Related article: Does Insulin Need to be Refrigerated? Essential Storage Tips!

What Happens If Insulin is Left Out of the Fridge?

Insulin is very sensitive to environmental storage conditions, particularly light and temperature. To maintain its stability and extend its shelf life, it must be refrigerated before use.

Typically, all types and brands of insulin- whether they come in vials, pens, or cartridges- must be stored in the refrigerator, ideally between 2°C and 8°C.

Once opened or removed from the fridge, insulin can be stored at room temperature, generally for about a month, provided it's never exposed to temperatures above 25°C, or 30°C for some brands.

Temperature fluctuations are a major concern as they can significantly degrade your insulin. When insulin is left out or exposed to high temperatures, its protein structure can break down, making it less effective or entirely ineffective in controlling your blood sugar levels. This degradation process accelerates at higher temperatures.

Related article: What Happens If Insulin Gets Warm? Essential Safety Tips!

How Long Can Insulin be Left Out?

The stability of insulin when left out depends on its type and brand.

Most manufacturers of insulin types and brands available in Canada state that insulin can remain out of the fridge for about 28 days without significant loss of potency. However, this can vary, as some brands or formulation may allow up to 56 days at room temperature.

Most insulins should never be exposed to temperatures higher than 25°C, though some may tolerate excursions at 30°C. Make sure to check the storage instructions for your specific brand and type of insulin!

Can You Use Insulin That's Been Left Out?

The effects of temperature on insulin occur gradually.

Leaving insulin out for an hour isn't the same thing as leaving it out overnight or for extended periods like 12 hours.

Moreover, it all depends on the ambient temperature too. Leaving your insulin out when it's only 15°C won't have the same detrimental effects as leaving it out on a much warmer day.

These duration and temperature differences significantly influence the rate at which insulin degrades and loses its efficacy.

Short Periods (1 to 2 Hours)

If your insulin has only been out of the fridge for a couple of hours and the room temperature was controlled (not too hot), it is generally safe to use. In that case, make sure to use it within 28 days (or check specific storage requirements for your insulin).

However, if your insulin is accidentally left out at temperatures above 25°C, or 30°C for some brands, even for a short period, it can rapidly degrade.

If it's 35°C in the room or if the insulin is left in direct sunlight, it's likely ruined, even within an hour.

Long Periods (12 Hours or Overnight)

When insulin has been left out for 12 hours or more, caution is advised. If the room was at a temperature below 25°C it is still safe to use within 28 days (or check specific duration for your insulin).

However, if the temperature was above 25°C or 30°C for some insulins, your insulin isn't safe for use anymore. You should dispose of it and take a new vial or pen from the refrigerator.

When in doubt, it is safer to avoid using insulin that has been left out for too long, especially if you're unsure about the temperature conditions it was exposed to.

Always inspect the insulin for any changes in color or clarity - any cloudiness or discolouration may mean the insulin has gone bad.

Related article: Can Insulin Go Bad? How To Tell and Symptoms To Watch For!

If you experience unusually high blood sugar levels, it may also be a sign your insulin isn't working as good as it should. It's best to consult your healthcare provider rather than risk using bad insulin and compromise your blood glucose control.

Remember, managing diabetes effectively involves meticulous attention to detail, and how you store your insulin plays a crucial role in this daily challenge.

Always have a backup plan for storing your insulin, especially when traveling or in unfamiliar settings!

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We'd Love to Hear From You!

Please share your comments, questions, and stories below to help us all learn more about living with diabetes and insulin!

November 22, 2024

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The information presented in this article and its comment section is for informational purposes only and is not intended as a replacement for professional medical advice. Always consult with a qualified healthcare provider for any medical concerns or questions you may have.